Used AB SCIEX / APPLIED BIOSYSTEMS / ABI / MDS SCIEX MagMax Express-96 #293597779 for sale

AB SCIEX / APPLIED BIOSYSTEMS / ABI / MDS SCIEX MagMax Express-96 is an automated whole genome amplification (WGA) platform designed for High Throughput Screening (HTS) applications. The platform is used to automate the routine duplicate SNP genotyping of thousands of genomic samples with high-throughput instruments. ABI MagMax Express-96 is based on a 96-well microplate format, allowing for extraction and amplification of nucleic acids from 96 samples simultaneously. This can greatly reduce the time and effort associated with manual sample processing. AB SCIEX MagMax Express-96 has been designed with a modular workflow for successful and reliable WGA of genomic samples. This workflow consists of the reagent setup, sample lysis, gel fill, WGA lysis and reaction, hot start, and post-amplification analysis. The platform's reagent setup is set up with optimized buffers and enzymes which enable efficient extraction of both genomic DNA (gDNA) and total RNA (tRNA) from a variety of sample sources. The sample lysis step is then used to facilitate high quality gDNA extraction, while the gel fill step prepares the samples for successful subsequent WGA lysis. The WGA lysis and reaction step is based on a combination of two technologies: direct nucleic acid detection (DNAD) and polymerase chain reaction (PCR). The DNAD technology is used for direct detection of all entire genome copies, allowing for detection of desired genetic markers and providing an unbiased approach for SNP genotyping. The PCR technology is utilized to amplify all of the extracted genome, which ensures successful amplification of desired genetic markers. Finally, the platform's hot start reaction ensures successful template amplification and prevents false-positive results. Post-amplification, the amplified samples can be easily analyzed with a variety of techniques, such as agarose gel electrophoresis, Real-Time PCR (qPCR), and High-Resolution Melt (HRM) Analysis. Overall, MDS SCIEX MagMax Express-96 provides a highly efficient platform for performing high-throughput WGA of genomic samples. The platform's modular workflow streamlines routine SNP genotyping analysis, and offers quick, reliable results. Furthermore, APPLIED BIOSYSTEMS MagMax Express-96 offers detection of all entire genome copies, ensuring accurate analysis of desired genetic markers.