Used GE HEALTHCARE LIFE SCIENCES Biacore 3000 #9053960 for sale

GE HEALTHCARE LIFE SCIENCES Biacore 3000 is a flexibly configured and user-friendly biacore technology platform designed to study biomolecular interactions with high precision, speed, sensitivity, and reproducibility. This advanced, automated equipment enables users to rapidly access detailed binding kinetic information, determine molecular identity, and assess the binding or functional behavior of a wide range of biomolecules in cleaved, non-cleaved, and membrane-associated states. Biacore 3000 platform consists of a computer-controlled flow cell, containing up to 7084 nanowells, which allow real-time analyte immobilization and act as a platform for label-free, surface plasmon resonance (SPR) technology. It also features a nanospray device to apply protein contents to the detector surface, a variety of flow cells to meet the needs of different assays, pipette tips, and additional assays and accessories such as detection reagents, data processing and control software. Using a single-cycle data analysis algorithm, GE HEALTHCARE LIFE SCIENCES Biacore 3000 platform quickly and accurately determines a wide range of binding constants, which include both kinetic and associative constants. These range from basic binding constants such as association and dissociation rate constants, to more complex parameters such as the on-rate of a protein-target interaction. Additionally, the system can be used to monitor anti-protein/anti-ligand concentration-dependent effects. The unit is designed for sample volumes of 1-10 µL and over a wide range of concentrations, and can analyze samples with low and variable analyte concentrations. Its temperature control allows for reliable detection and analysis of samples under varying temperatures (4°C, 10°C, 30°C, and 37°C). It also features a syringe-based fluid delivery machine, providing consistently high-precision flow rate control. Additionally, Biacore 3000 uses robust hardware and an intuitive user interface, which simplifies operation, and includes a touchscreen display with full graphical user interface. To analyze data as it is gathered, GE HEALTHCARE LIFE SCIENCES Biacore 3000 includes advanced analysis software, and can export data in a variety of formats, enabling easy integration with a wide variety of downstream small molecule and biopharmaceutical applications.