Used MOLECULAR DEVICES FLIPR #165380 for sale

MOLECULAR DEVICES FLIPR® is a microplate-based lab instrument designed to measure drug responses in living cells. The "FLIPR" stands for Fluorescent Imaging Plate Reader, and is a powerful tool for high-throughput drug screening, evaluation, and assay design. With this instrument, researchers can simultaneously measure receptor-specific changes in multiple cell lines using different cellular assays in just a few hours. MOLECULAR DEVICES FLIPR's innovative design includes both hardware and software systems. The hardware consists of a remote control laser, a Xenon flash lamp, a patented emission filter wheel, and a megapixel CCD sensor for data acquisition. Together, the hardware creates the precise environment necessary for the activation and reaction of fluorescently-tagged proteins. The software system provides control of the instrument parameters and analyzes the data collected from the sensor. It has powerful algorithms designed to recognize subtle changes in fluorescence in response to drugs, as well as data analysis and visualization tools. The use of FLIPR can provide scientists with valuable information about the efficacy of pharmaceutical compounds. This enables drug developers to identify compounds that interact with a target receptor. In addition, this information can be used to identify new drug candidates and develop new therapies. MOLECULAR DEVICES FLIPR is also used to assess safety profiles of agents. By monitoring the real-time cellular health of exposed cells and measuring their response to test compounds, the instrument can generate results that can be used to establish metabolic and toxicological profiles of compounds. Ultimately, this information can be used to determine dosages for agents. FLIPR is also useful for conducting research in cell-based systems. A variety of applications are available, such as measuring cytotoxicity, tracking the expression and localization of proteins, and understanding the effects of compounds on cellular signaling cascades. Furthermore, MOLECULAR DEVICES FLIPR can play an important role in identifying the off-target effects of drug compounds. This can help researchers understand any undesired effects on non-targeted receptor populations. Overall, FLIPR is a valuable laboratory tool for drug discovery and development. It offers scientists a quick, automated, and sensitive way to assess the activity of drug compounds, as well as their safety profiles. MOLECULAR DEVICES FLIPR's comprehensive hardware and software system also enables researchers to conduct a variety of cell-based experiments. With its ability to detect subtle changes in fluorescence, FLIPR can provide researchers with valuable data to aid in the design and synthesis of better, more effective drugs.