Used NANOMETRICS / BIO-RAD / ACCENT / CIPHERGEN SELDI-TOF MS #9106664 for sale

NANOMETRICS / BIO-RAD / ACCENT / CIPHERGEN SELDI-TOF MS (Surface Enhanced Laser Desorption/Ionization); Time-of-Flight Mass Spectrometry) is a type of mass spectrometry instrument designed to detect small molecules from diverse samples. The technology is based on the principles of matrix assisted laser desorption/ionization (MALDI). Unlike MALDI however, SELDI does not require crystallization or pre-dissociation of the sample before analysis. Instead, a chip containing a chemically-tailored sample preparation surface is utilized in order to capture and concentrate the analytes of interest onto an appropriate matrix. The overall measurement process of ACCENT SELDI-TOF MS instrument is divided into four stages. First, sample collection and preparation takes place, where the sample is dissolved and applied to the sample prep chip. This chip is then inserted into the instrument where it is analyzed in the second stage, which involves the laser desorption and ionization of the sample. In the third stage, a Time-of-Flight (TOF) mass spectrometer captures and sorts the sample's ions. Finally, the results of the analysis are processed and evaluated by the computer, and a spectrum of the sample composition is generated. The advantages of BIO-RAD SELDI-TOF MS are that the instrument can be used to detect a variety of molecules from different sample types, including tissue, urine, and serum. Additionally, the quantitative nature of the method, coupled with its high sensitivity, makes it a useful tool for studying biomolecules. Furthermore, it can be used to analyze a wide range of sample sizes, from isolated molecules to purified proteins. In conclusion, SELDI-TOF MS is a versatile and sensitive spectrometer that can detect small molecules from different sample types in a quantitative manner. With its ease of operation and customizability, it is a useful tool for studying biomolecules and understanding the composition of various samples.