Used SEQUENOM MassARRAY Analyzer 4 #9219444 for sale

SEQUENOM MassARRAY Analyzer 4 is a highly advanced spectrometer designed to quantify mutant and wild-type alleles from genomic DNA samples. Developed by SEQUENOM, Inc., the MassARRAY technology in this device combines simple PCR reactions with mass spectrometry for highly reliable, quantitative genotyping. This model has a substantially improved user interface and faster operation than its predecessor, the MassARRAY Analyzer 3. MassARRAY Analyzer 4 leverages a custom-designed 384 well tray-based autosampler filled with sample PCR reactions. The advanced sample delivery system ensures efficient and accurate mixing of samples, while also minimizing the exposure of samples to extreme temperatures or other environmental perturbations. The device is equipped with a dedicated laser source for direct-infrared (DIR) detection of fluorescence-labeled allele-specific extension products in the sample PCR reactions. Using this specialized laser, SEQUENOM MassARRAY Analyzer 4 is able to detect and differentiate among multiple alleles or genotypes in a single sample. The laser light is focused on a quadrant mirror and directed to a second mirror mounted on a precision robotic actuator. The mirror is then used to scan the sample PCR reactions for fluorescence signals, which are then detected by a silicon-based avalanche photodiodes (APD). MassARRAY Analyzer 4 also comes equipped with a powerful software program, developed by SEQUENOM, Inc., which helps automate the genotyping protocol. This software allows users to design customized genotyping assays and control all aspects of the PCR reaction and genotyping process, as well as store and analyze genotyping data. SEQUENOM MassARRAY Analyzer 4 is able to accurately determine DNA copy number, single nucleotide polymorphisms (SNPs), insertion/deletion mutations, as well as other genetic variations. In addition to its impressive accuracy and specificity, the instrument offers great flexibility, as it can run multiple assays simultaneously with minimal labor input. Overall, MassARRAY Analyzer 4 is a highly advanced and reliable spectrometer for genotyping, offering considerable cost savings and accuracy when compared to other available solutions.