Used SHIMADZU LCMS #9109023 for sale
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SHIMADZU LCMS (Liquid Chromatography-Mass Spectrometer) is a high-performance analytical instrument used for chemical characterization and identification of compounds. LCMS equipment combines the separation strength of liquid chromatography (LC) with the analytical power of mass spectrometry (MS). This combination enables users to analyze complex samples from multiple sample types, including biological and environmental samples. SHIMADZU LCMS utilizes a flow-through system, where liquid samples are injected into LCMS unit, separated by a column, passed into an ionization device, and then detected by the mass spectrometer. SHIMADZU LCMS machine consists of five main components: HPLC (High Performance Liquid Chromatography), APCI (Atmospheric Pressure Chemical Ionization), MS (Mass Spectrometer), ESI (Electrospray Ionization) and CAD (Continuous Analysis Tool). The HPLC is used to separate components of a sample through a column coated with a stationary phase material. The mobile phase is a liquid that passes through the column, and the compounds in the sample are separated based on their affinity for the stationary phase. The APCI is a form of atmospheric pressure ionization that is used in LCMS asset for more efficient ionization in positive-ion and negative-ion detection modes. The APCI ionizes troublesome, non-volatile compounds that are difficult to detect with ESI. The mass spectrometer is used to detect and quantify the separated compounds in the sample. It works by converting the components into gaseous ions and accelerating them using both an electrostatic field and a magnetic field. The ions then pass through a detector, which measures the ion's m/z ratio (mass/charge), to determine the mass of the compound. The ESI is a soft ionization method that very effectively produces ions from compounds with multiple functional groups. It works by passing the sample through a narrow viscous stream of liquid containing the mobile phase from the HPLC and spraying droplets into a heated gas environment. Finally, the CAD (Continuous Analysis Model) is used to control, monitor and analyze information generated by SHIMADZU LCMS. It is a control equipment that allows users to customize LCMS's performance and settings such as pressure, temperature, flow rate, and other factors. Overall, SHIMADZU LCMS is an efficient and powerful high-performance analytical instrument used for chemical characterization. It is suitable for a wide range of applications, including environmental monitoring, food and beverage safety analysis as well as pharmaceutical and drug development research.
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