Used THERMO FISHER SCIENTIFIC Exactive #9237892 for sale

THERMO FISHER SCIENTIFIC Exactive is an advanced high-resolution, ultrafast mass spectrometer with unprecedented sensitivity and robustness. The instrument uses an Orbitrap mass analyzer to provide improved selectivity, accuracy, and speed over traditional time-of-flight (TOF) instruments. Relative to TOF instruments, Exactive is able to achieve a higher resolution with a wider dynamic range and more rapid data acquisition. This makes it particularly suitable for detailed, reproducible characterization of complex mixtures. The analyzer is based on a Fourier-transform-detection system with an electrode array, known as an Orbitrap. A linear voltage ramp is applied to the electrode array to induce a rapid increase in the magnetic field stabilizing the stored ions. Charged particles in the Orbitrap analyzer deflect and then spiral toward the center under electromagnetic forces, accumulating in the center and focusing near the central electrodes. Subsequently, a small electric field is applied to the electrodes, causing the ions to spread out as a Fourier transform. This converts the radial movement of the ions into a frequency spectrum that is detected by an array of detector plates outside the analyzer. The mass of each ion is determined by its cyclotron frequency. THERMO FISHER SCIENTIFIC Exactive incorporates efficient electron and gas-phase ionization sources for sample analysis, while also allowing users to take full advantage of in-source collision-induced dissociation (CID) via the SideJet interface, drastically improving data quality. The system can achieve high-quality data acquisition at data speeds fast enough to enable real-time analysis, providing the flexibility to rapidly adapt the method to specific analyte characteristics. The instrument offers maximum performance when used with the latest data acquisition software, Thermo Scientific Proteome Discoverer. This software provides extensive customization of scan programs and sophisticated data analysis to support proteomics and metabolomics applications. Thanks to its high sensitivity and wide dynamic range, Exactive is an ideal mass spectrometer for researchers seeking detailed characterization of complex mixtures. As well as providing access to all principles of mass spectrometric site analysis, its speed and flexibility allows it to efficiently acquire comprehensive data for improved genome-wide expression studies.