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ID: 9176105
Benchtop mass spectrometer
OS: Windows XP
ORBITRAP High-performance benchtop LC-MS
Specifications:
Mass range: m/z 50 - 4000
Resolution:
100,000 at m/z 200 at a scan rate of 1 Hz
Minimum resolution 10,000 at m/z 200 at a scan rate of 10 Hz
Mass accuracy:
< 5 ppm with external calibration
< 2 ppm using internal calibration
Polarity switching: One full cycle in < 1 sec
Dynamic range: > 4,000 within a single scan
MS Scan power: Full scan and all ion fragmentation by HCD
Scan rate: 1-10 Hz
Analog inputs:
Analog input (0-1 V)
Analog (0-10 V)
ORBITRAP Mass analyzer:
Gas (nitrogen) filled C-trap
Highly efficient ion transfer optics to ORBITRAP analyzer
Straight multipole collision cell for HCD
Orbital trap with 5kV central electrode voltage
Low-noise image current pre-amplifier 16-bit signal digitization
Ultra fast real-time data acquisition
Instrument control system.
THERMO SCIENTIFIC Exactive is a high performing spectrometer developed by Thermo Fisher Scientific, the world leader in analytical instrument technology. Exactive's architecture combines a high-resolution (HR) Orbitrap mass analyzer with the newest generation of ETD technology, providing unparalleled versatility and sensitivity for LC-MS/MS research. The combination of technologies in THERMO SCIENTIFIC Exactive system delivers a wide range of benefits including high mass accuracy, increased selectivity, elevated sensitivity, and rapid run times. The HR Orbitrap mass analyzer provides an extended mass range from low to ultra-high mass values, as well as accurate mass resolution and ultra-high resolution for accurate isotope pattern measurement. At the same time, the ETD technology provides a higher degree of selectivity and enhanced sensitivity even for complex peptide mixtures. This is achieved by using the charge-state dependent dissociation processes of HCD and CAD (collisional activation dissociation), resulting in better sequence coverage. Exactive's software platform includes a comprehensive data processing suite that makes data acquisition, interpretation, and reporting simple and fast. An integrated suite of search algorithms is included, enabling users to easily search protein and peptide databases. Automated peak-picking algorithms assist in extracting useful information from LC-MS data, and various metrics support the scoring of data hits. Data can be visualized using a customizable graphical user interface, and the system can output data in a variety of formats, including an open Microsoft Excel file format for easy sharing and comparison. THERMO SCIENTIFIC Exactive also incorporates a number of other features for increased efficiency, such as the autopause function that stops data acquisition when a previously chosen concentration limit is reached, and a built-in software-controlled auto-sampler for batch processing of samples. Additionally, Exactive is designed to maximize operator safety, with a low-noise housing, low-maintenance peristaltic fluidics, and an integrated protective filter system. In sum, THERMO SCIENTIFIC Exactive is a versatile, high-performance spectrometer designed for multidimensional LC-MS/MS research. Its combination of HR Orbitrap mass analyzer and ETD technologies provides unparalleled sensitivity and selectivity, making it ideal for complex research applications. Built-in safety and automation features further enhance its use, making it an excellent choice for the modern lab.
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